TxBench Antibody Discovery V1 (100 evaluations)
Science · 2026-10-09
The October 9, 2026 published V1 antibody-discovery cohort contains 100 evaluation records, reduced from the previously published 137-record cohort. Macro-mean pass rates are kept separate from that earlier cohort.
Top models (higher is better)
| Model | Score |
|---|---|
| Claude Sonnet 5.5 | 57.3 |
| GPT-6 Astra | 56.0 |
| Grok 4.6 | 53.0 |
| Grok 4.7 | 52.0 |
| Gemini 3.7 Flash | 50.7 |
| GPT-6.1 Sol | 49.7 |
| Gemini 3.8 Flash | 49.0 |
| Claude Opus 5 | 48.7 |
| GPT-6 Sol | 43.3 |
| DeepSeek V4.1 Flash | 39.7 |
| GPT-5.6 Sol | 37.3 |
| Opus 4.7 | 36.0 |
| Opus 4.8 | 35.3 |
| Kimi K3 | 35.3 |
| GPT-6 Luna | 34.0 |
| GPT-5.5 | 33.0 |
| Sonnet 5 | 32.0 |
| Sonnet 4.6 | 26.3 |
| GPT-5.6 Luna | 19.3 |
| Nemotron 3.5 Lightning 30B A3B (precision unspecified) | 16.0 |
| Claude Opus 5.5 | 8.3 |