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BenchBench-Cloning

Science · 2026-10-23

65 molecular-cloning planning tasks from Benchling and DNAForge grounded in sequence records, lab notebooks and published experiments: 50 protocol-development tasks (pass if every deterministic check passes; ten attempts each) and 15 construct-design tasks (pass if the final score is at least 0.9; five attempts each). Agents run in their native harnesses in sandboxes with network access limited to the model provider. The score is the task-weighted aggregate pass rate (50/65 protocol, 15/65 construct), in percent.

Top models (higher is better)

ModelScore
GPT-6 Astra30.6
GPT-6.1 Sol22.2
Claude Opus 5.520.5
Gemini 4 Argon18.8
Kimi K311.1
Grok 4.710.9
Gemini 3.8 Flash10.8
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